We are seeking a bioinformatics software engineer to join Vertex’s research site in Boston, MA. This position is part of a growing global Computational Genomics team focused on developing novel, innovative gene editing and genetic therapy treatments for serious human diseases. A key task will be to develop robust computational software tools and systems that will be leveraged for the development of genetic therapies. Strong software engineering skills, with an understanding of how to design and implement production-quality code, are critical. While no medical, genomics or scientific background is required, a passion for playing a critical role in the development of transformative therapies is essential.
Collaborate with project teams and computational biologists to understand scientific needs and define specifications
Design and build state-of-the-art, generalizable, and robust software tools to enable the lifecycle of genetic therapy development
Develop automated tests, including unit, integration, functional, regression, and scalability testing
Optimize algorithms and methods as needed to facilitate rapid analysis of large-scale data from high-throughput experiments
Compare multiple implementations to answer the same scientific problem to identify the best one for our needs, considering speed, accuracy, and scalability
Provide clear documentation and training to computational biologists using your tools
Communicate your work with both technical and non-technical stakeholders
Work in a team-oriented development environment, including group design and code reviews
Develop, champion, and evolve standards and best practices of software engineering, such as version control, modular software design, testing, code style standards, and development methodologies
B.S., M.S., or Ph.D. in computer science, computational biology, bioinformatics, or a related field
3+ years of Software Development industry experience is preferred, though exceptional candidates with less experience will be considered
Experience developing, testing, and delivering production-quality software in a team programming environment in a timely manner
Strong programming skills, with the ability to write clear, maintainable, and well-tested code
Expertise in Linux/Unix environments, Python, and R
Detail-oriented and self-motivated approach to problem solving with excellent reasoning skills
A positive attitude that enthusiastically tackles and overcomes challenges, with excellent organizational and time-management skills to prioritize needs and get things done
A team-oriented growth mindset that welcomes feedback from others and supports other team members
Experience in the analysis, visualization, and interpretation of genomic and next-generation sequencing (NGS) data and familiarity with programs for analysis of sequencing data
Experience with key data analysis technologies, such as high-performance and cloud computing, containers for application deployment (e.g. Docker), and tools for interactive data exploration and documentation (e.g. R Shiny, Jupyter)
Scientific understanding of gene editing, the role of genetic variation in human disease, molecular biology, and cellular biology
Expertise in applied statistics and machine learning
Internal Number: 12150BR
About Vertex Pharmaceuticals
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious and life-threatening diseases. We discovered and developed the first medicines to treat the underlying cause of cystic fibrosis (CF), a rare, life-threatening genetic disease. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases.
Founded in 1989 in Cambridge, Massachusetts, our corporate headquarters is now located in Boston's Innovation District, and our international headquarters is in London, United Kingdom. We currently employ approximately 2,500 people in the United States, Europe, Canada, Australia and Latin America with nearly two-thirds of our staff dedicated to research and development.
Vertex is consistently recognized as one of the industry’s top places to work by Science Magazine, The Boston Globe, Boston Business Journal and the San Diego Business Journal. Our research and medicines have also received esteemed recognitions, including the Robert J. Beall Therapeutics Development Award, the French Prix Galien and t...he British Pharmacological Society awards. For additional information and the latest updates from the Company, please visit www.vrtx.com.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com.